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A New Cephalosporin with a Dual Mode of Action

A cephalosporin, (6R,7R)-7-[(2R)-2-hydroxy-2-phenylacetamido]-3-(pyrid-2-yl-N-oxide) thiomethylceph-3-em-4-carboxylic acid (MCO), that could lead to a novel approach to the problem of β-lactamase destruction is described. The compound is slightly more resistant to some β-lactamases than is cephaloth...

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Bibliografiske detaljer
Main Authors: O'Callaghan, Cynthia H., Sykes, R. B., Staniforth, Susan E.
Format: Artigo
Sprog:Inglês
Udgivet: 1976
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC429729/
https://ncbi.nlm.nih.gov/pubmed/984765
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