Hydroxyquinolines Inhibit Ribonucleic Acid-Dependent Deoxyribonucleic Acid Polymerase and Inactivate Rous Sarcoma Virus and Herpes Simplex Virus

8-Hydroxyquinoline and several of its derivatives inactivate the transforming ability of Rous sarcoma virus and inhibit its ribonucleic acid-dependent deoxyribonucleic acid polymerase activity. The copper complex of these metal-binding ligands is as active as the free ligand. The activity of the 8-h...

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Bibliografiske detaljer
Main Authors: Rohde, Wolfgang, Mikelens, Peter, Jackson, Jean, Blackman, Jane, Whitcher, Jack, Levinson, Warren
Format: Artigo
Sprog:Inglês
Udgivet: 1976
Fag:
Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC429727/
https://ncbi.nlm.nih.gov/pubmed/185949
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