Hydroxyquinolines Inhibit Ribonucleic Acid-Dependent Deoxyribonucleic Acid Polymerase and Inactivate Rous Sarcoma Virus and Herpes Simplex Virus

8-Hydroxyquinoline and several of its derivatives inactivate the transforming ability of Rous sarcoma virus and inhibit its ribonucleic acid-dependent deoxyribonucleic acid polymerase activity. The copper complex of these metal-binding ligands is as active as the free ligand. The activity of the 8-h...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Rohde, Wolfgang, Mikelens, Peter, Jackson, Jean, Blackman, Jane, Whitcher, Jack, Levinson, Warren
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1976
Assuntos:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429727/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/185949/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.10.2.234
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