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SRT1720 induces lysosomal-dependent cell death of breast cancer cells

SRT1720 is an activator of SIRT1, a NAD(+) dependent protein and histone deacetylase that plays an important role in numerous biological processes. Several studies have illustrated that SRT1720 treatment could improve metabolic conditions in mouse models and a study in cancer where SRT1720 caused in...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Lahusen, Tyler J., Deng, Chu-Xia
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297239/
https://ncbi.nlm.nih.gov/pubmed/25411356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0584
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