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Spinal cord stimulation reduces mechanical hyperalgesia and glial cell activation in animals with neuropathic pain

Spinal cord stimulation (SCS) is used to manage chronic intractable neuropathic pain. We examined parameters of SCS in rats with spared nerve injury by modulating frequency (4Hz vs. 60Hz), duration (30m vs. 6h), or intensity (50%, 75%, or 90% MT). To elucidate potential mechanisms modulated by SCS,...

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Publicat a:Anesth Analg
Autors principals: Sato, Karina L., Johanek, Lisa M., Sanada, Luciana S., Sluka, Kathleen A.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297213/
https://ncbi.nlm.nih.gov/pubmed/24361846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000000047
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