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Spinal cord stimulation reduces mechanical hyperalgesia and glial cell activation in animals with neuropathic pain

Spinal cord stimulation (SCS) is used to manage chronic intractable neuropathic pain. We examined parameters of SCS in rats with spared nerve injury by modulating frequency (4Hz vs. 60Hz), duration (30m vs. 6h), or intensity (50%, 75%, or 90% MT). To elucidate potential mechanisms modulated by SCS,...

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Detalhes bibliográficos
Publicado no:Anesth Analg
Main Authors: Sato, Karina L., Johanek, Lisa M., Sanada, Luciana S., Sluka, Kathleen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297213/
https://ncbi.nlm.nih.gov/pubmed/24361846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000000047
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