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Relationship of a non-cystic fibrosis transmembrane conductance regulator-mediated chloride conductance to organ-level disease in Cftr(-/-) mice.

Although loss of cystic fibrosis transmembrane conductance regulator (CFTR)-mediated Cl- channel function is common to all epithelia in cystic fibrosis (CF) patients, the severity of disease varies in different organs. We hypothesized that differences in disease severity in CF relate to the expressi...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Clarke, L L, Grubb, B R, Yankaskas, J R, Cotton, C U, McKenzie, A, Boucher, R C
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42972/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7507247/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.2.479
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