The Oncogene LRF Stimulates Proliferation of Mesenchymal Stem Cells and Inhibits Their Chondrogenic Differentiation

Objective. The oncogene leukemia/lymphoma-related factor (LRF) enhances chondrosarcoma proliferation and malignancy. This study aimed to investigate the roles of LRF in chondrogenic differentiation of primary human bone marrow–derived mesenchymal stem cells (BMSCs). Design. LRF was overexpressed in...

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Bibliographic Details
Published in:Cartilage
Main Authors: Yik, Jasper H.N., Li, Huan, Acharya, Chitrangada, Kumari, Ratna, Fierro, Fernando, Haudenschild, Dominik R., Nolta, Jan, Di Cesare, Paul E.
Format: Artigo
Language:Inglês
Published: SAGE Publications 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297155/
https://ncbi.nlm.nih.gov/pubmed/26069677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947603513497570
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