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CHK2 kinase in the DNA damage response and beyond
The serine/threonine kinase CHK2 is a key component of the DNA damage response. In human cells, following genotoxic stress, CHK2 is activated and phosphorylates >20 proteins to induce the appropriate cellular response, which, depending on the extent of damage, the cell type, and other factors, co...
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| Published in: | J Mol Cell Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4296918/ https://ncbi.nlm.nih.gov/pubmed/25404613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mju045 |
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