TGF-β Suppresses COX-2 Expression by Tristetraprolin-Mediated RNA Destabilization in A549 Human Lung Cancer Cells

PURPOSE: Overexpression of cyclooxygenase 2 (COX-2) is thought to promote survival of transformed cells. Transforming growth factor β (TGF-β) exerts anti-proliferative effects on a broad range of epithelial cells. In the current study, we investigated whether TGF-β can regulate COX-2 expression in A...

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發表在:Cancer Res Treat
Main Authors: Kang, Soyeong, Min, Ahrum, Im, Seock-Ah, Song, Sang-Hyun, Kim, Sang Gyun, Kim, Hyun-Ah, Kim, Hee-Jun, Oh, Do-Youn, Jong, Hyun-Soon, Kim, Tae-You, Bang, Yung-Jue
格式: Artigo
語言:Inglês
出版: Korean Cancer Association 2015
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296860/
https://ncbi.nlm.nih.gov/pubmed/25544576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2013.192
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