CD200 in CNS tumor-induced immunosuppression: the role for CD200 pathway blockade in targeted immunotherapy

BACKGROUND: Immunological quiescence in the central nervous system (CNS) is a potential barrier to immune mediated anti-tumor response. One suppressive mechanism results from the interaction of parenchyma-derived CD200 and its receptor on myeloid cells. We suggest that CD200/CD200R interactions on m...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Moertel, Christopher L, Xia, Junzhe, LaRue, Rebecca, Waldron, Nate N, Andersen, Brian M, Prins, Robert M, Okada, Hideho, Donson, Andrew M, Foreman, Nicholas K, Hunt, Matthew A, Pennell, Christopher A, Olin, Michael R
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296547/
https://ncbi.nlm.nih.gov/pubmed/25598973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-014-0046-9
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