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A novel IgM–H-Ficolin complement pathway to attack allogenic cancer cells in vitro

The pentameric serum IgMs are critical to immune defense and surveillance through cytotoxicity against microbes and nascent cancer cells. Ficolins, a group of oligomeric lectins with an overall structure similar to C1q and mannose-binding lectin (MBL) participate in microbe infection and apoptotic c...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lei, Xiaoying, Liu, Chaoxu, Azadzoi, Kazem, Li, Cuiling, Lu, Fan, Xiang, An, Sun, Jianbin, Guo, Yanhai, Zhao, Qingchuan, Yan, Zhen, Yang, Jinghua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296296/
https://ncbi.nlm.nih.gov/pubmed/25592840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07824
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