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A novel IgM–H-Ficolin complement pathway to attack allogenic cancer cells in vitro
The pentameric serum IgMs are critical to immune defense and surveillance through cytotoxicity against microbes and nascent cancer cells. Ficolins, a group of oligomeric lectins with an overall structure similar to C1q and mannose-binding lectin (MBL) participate in microbe infection and apoptotic c...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4296296/ https://ncbi.nlm.nih.gov/pubmed/25592840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07824 |
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