Super-resolution imaging reveals that loss of the C-terminus of connexin43 limits microtubule plus-end capture and Na(V)1.5 localization at the intercalated disc

AIMS: It is well known that connexin43 (Cx43) forms gap junctions. We recently showed that Cx43 is also part of a protein-interacting network that regulates excitability. Cardiac-specific truncation of Cx43 C-terminus (mutant ‘Cx43D378stop’) led to lethal arrhythmias. Cx43D378stop localized to the i...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Agullo-Pascual, Esperanza, Lin, Xianming, Leo-Macias, Alejandra, Zhang, Mingliang, Liang, Feng-Xia, Li, Zhen, Pfenniger, Anna, Lübkemeier, Indra, Keegan, Sarah, Fenyö, David, Willecke, Klaus, Rothenberg, Eli, Delmar, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296112/
https://ncbi.nlm.nih.gov/pubmed/25139742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu195
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