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Super-resolution fluorescence microscopy of the cardiac connexome reveals plakophilin-2 inside the connexin43 plaque

AIMS: Cell function requires formation of molecular clusters localized to discrete subdomains. The composition of these interactomes, and their spatial organization, cannot be discerned by conventional microscopy given the resolution constraints imposed by the diffraction limit of light (∼200–300 nm...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Agullo-Pascual, Esperanza, Reid, Dylan A., Keegan, Sarah, Sidhu, Manavjeet, Fenyö, David, Rothenberg, Eli, Delmar, Mario
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797628/
https://ncbi.nlm.nih.gov/pubmed/23929525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt191
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