FSL-1, a Toll-like Receptor 2/6 Agonist, Induces Expression of Interleukin-1α in the Presence of 27-hydroxycholesterol

We investigated the question of whether cholesterol catabolite can influence expression of inflammatory cytokines via Toll-like receptors (TLR) in monocytic cells. Treatment of THP-1 monocytic cells with 27-hydroxycholesterol (27OHChol) resulted in induction of gene transcription of TLR6 and elevate...

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Veröffentlicht in:Korean J Physiol Pharmacol
Hauptverfasser: Heo, Weon, Kim, Sun-Mi, Eo, Seong-Kug, Rhim, Byung-Yong, Kim, Koanhoi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Physiological Society and The Korean Society of Pharmacology 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296036/
https://ncbi.nlm.nih.gov/pubmed/25598661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2014.18.6.475
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