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Red cells from ferrochelatase-deficient erythropoietic protoporphyria patients are resistant to growth of malarial parasites

Many red cell polymorphisms are a result of selective pressure by the malarial parasite. Here, we add another red cell disease to the panoply of erythrocytic changes that give rise to resistance to malaria. Erythrocytes from individuals with erythropoietic protoporphyria (EPP) have low levels of the...

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: Smith, Clare M., Jerkovic, Ante, Puy, Hervé, Winship, Ingrid, Deybach, Jean-Charles, Gouya, Laurent, van Dooren, Giel, Goodman, Christopher Dean, Sturm, Angelika, Manceau, Hana, McFadden, Geoffrey Ian, David, Peter, Mercereau-Puijalon, Odile, Burgio, Gaétan, McMorran, Brendan J., Foote, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296013/
https://ncbi.nlm.nih.gov/pubmed/25414439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-567149
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