Deep sequencing identifies genetic heterogeneity and recurrent convergent evolution in chronic lymphocytic leukemia

Recent high-throughput sequencing and microarray studies have characterized the genetic landscape and clonal complexity of chronic lymphocytic leukemia (CLL). Here, we performed a longitudinal study in a homogeneously treated cohort of 12 patients, with sequential samples obtained at comparable stag...

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Publicado en:Blood
Autores principales: Ojha, Juhi, Ayres, Jackline, Secreto, Charla, Tschumper, Renee, Rabe, Kari, Van Dyke, Daniel, Slager, Susan, Shanafelt, Tait, Fonseca, Rafael, Kay, Neil E., Braggio, Esteban
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2015
Materias:
Lymphoid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296010/
https://ncbi.nlm.nih.gov/pubmed/25377784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-580563
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