Uptake of Metronidazole and Its Effect on Viability in Trichomonads and Entamoeba invadens Under Anaerobic and Aerobic Conditions

[(14)C]metronidazole used at the chemotherapeutic concentration of 10 μg/ml is taken up rapidly by the anaerobic protozoa Tritrichomonas foetus, Trichomonas vaginalis, and Entamoeba invadens kept under anaerobic conditions. It can be calculated that within 30 to 60 min the intracellular concentratio...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	MÜller, MiklÓs, Lindmark, Donald G.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1976
Soggetti:	Chemistry; Mechanisms of Action and Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429600/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1083712/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.9.4.696
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