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Lethal and Mutagenic Effects of 5-Iodouracil on Bacteriophage T4td8rII

Evidence was obtained which indicates that the lethal effect of 5-iodouracil (IUra) on bacteriophage T4 is not due to a mutagenic process. T4td8rII (thymine requiring, rapid lysis) double mutants were constructed. Reversion of T4td8rII to r(+) was measured. First, reversion by growth in the presence...

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Bibliographic Details
Main Authors: Byrd, Daniel M., Prusoff, William H.
Format: Artigo
Language:Inglês
Published: 1977
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC351973/
https://ncbi.nlm.nih.gov/pubmed/848938
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