Carregant...
PRDM9 is a Major Determinant of Meiotic Recombination Hotspots in humans and mice
Meiotic recombination events cluster into narrow segments of the genome, defined as hotspots. Here, we demonstrate that a major player for hotspot specification is the Prdm9 gene. First, two mouse strains that differ in hotspot usage are polymorphic for the zinc finger DNA binding array of PRDM9. Se...
Guardat en:
| Publicat a: | Science |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4295902/ https://ncbi.nlm.nih.gov/pubmed/20044539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1183439 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|