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Two steps forward, one step back: determining XPD helicase mechanism by single-molecule fluorescence and high-resolution optical tweezers
XPD-like helicases constitute a prominent DNA helicase family critical for many aspects of genome maintenance. These enzymes share a unique structural feature, an auxiliary domain stabilized by an iron-sulphur (FeS) cluster, and a 5′-3′ polarity of DNA translocation and duplex unwinding. Biochemical...
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| Publicado en: | DNA Repair (Amst) |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4295835/ https://ncbi.nlm.nih.gov/pubmed/24560558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.01.013 |
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