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TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor

Detection of external irritants by head nociceptor neurons has deep evolutionary roots. Irritant-induced aversive behavior is a popular pain model in laboratory animals. It is used widely in the formalin-model, where formaldehyde is injected into the rodent paw, eliciting quantifiable nocifensive be...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Chen, Yong, Kanju, Patrick, Fang, Quan, Lee, Suk Hee, Parekh, Puja K., Lee, Whasil, Moore, Carlene, Brenner, Daniel, Gereau, Robert W., Wang, Fan, Liedtke, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295825/
https://ncbi.nlm.nih.gov/pubmed/25281928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2014.09.033
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