Modeling the influence of stromal microenvironment in the selection of ENU-induced BCR-ABL1 mutants by tyrosine kinase inhibitors

Tyrosine kinase inhibitors (TKIs) have profoundly changed the natural history of chronic myeloid leukemia (CML). However, acquired resistance to imatinib, dasatinib or nilotinib (1(st) and 2(nd) generation TKIs), due in part to BCR-ABL1 kinase mutations, has been largely described. These drugs are i...

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發表在:Oncoscience
Main Authors: Aggoune, Djamel, Tosca, Lucie, Sorel, Nathalie, Bonnet, Marie-Laure, Dkhissi, Fatima, Tachdjian, Gérard, Bennaceur-Griscelli, Annelise, Chomel, Jean-Claude, Turhan, Ali G
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2014
主題:
Research Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295758/
https://ncbi.nlm.nih.gov/pubmed/25593988
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