iPSC-Derived Hereditary Breast Cancer Model Reveals the BRCA1-Deleted Tumor Niche as a New Culprit in Disease Progression

Tumor progression begins when cancer cells recruit tumor-associated stromal cells to produce a vascular niche, ultimately resulting in uncontrolled growth, invasion, and metastasis. It is poorly understood, though, how this process might be affected by deletions or mutations in the breast cancer typ...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Portier, Lucie, Desterke, Christophe, Chaker, Diana, Oudrhiri, Noufissa, Asgarova, Afag, Dkhissi, Fatima, Turhan, Ali G., Bennaceur-Griscelli, Annelise, Griscelli, Frank
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866119/
https://ncbi.nlm.nih.gov/pubmed/33513753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031227
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