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Novel LIMK2 Inhibitor Blocks Panc-1 Tumor Growth in a mouse xenograft model

LIM kinases (LIMKs) are important cell cytoskeleton regulators that play a prominent role in cancer manifestation and neuronal diseases. The LIMK family consists of two homologues, LIMK1 and LIMK2, which differ from one another in expression profile, intercellular localization, and function. The mai...

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Vydáno v:Oncoscience
Hlavní autoři: Rak, Roni, Haklai, Roni, Elad-Tzfadia, Galit, Wolfson, Haim J., Carmeli, Shmuel, Kloog, Yoel
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295757/
https://ncbi.nlm.nih.gov/pubmed/25593987
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