Llwytho...
Development of a High Affinity, Non-covalent Biologic to Add Functionality to Fabs
Functionalization of monoclonal antibodies (mAbs) requires chemical derivatization and/or genetic manipulation. Inherent in these methods are challenges with protein heterogeneity, stability and solubility. Such perturbations could potentially be avoided by using a high affinity, non-covalent interm...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Sci Rep |
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Prif Awduron: | , , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Nature Publishing Group
2015
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4295097/ https://ncbi.nlm.nih.gov/pubmed/25588710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07817 |
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