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Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies
Capitalizing on their extraordinary specificity, monoclonal antibodies (mAbs) have become one of the most reengineered classes of biological molecules. A major goal in many of these engineering efforts is to add new functionality to the parental mAb, including the addition of cytotoxins and imaging...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3808661/ https://ncbi.nlm.nih.gov/pubmed/24101516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307309110 |
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