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Expanding the Ortholog Approach for Hemophilia Treatment Complicated by Factor VIII Inhibitors
BACKGROUND: The formation of neutralizing antibodies (inhibitors) directed against human coagulation factor VIII (hFVIII) is a life-threatening pathogenic response that occurs in 20–30% of severe congenital hemophilia A patients and 0.00015% of remaining population (i.e. acquired hemophilia A). Inte...
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| Vydáno v: | J Thromb Haemost |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4295011/ https://ncbi.nlm.nih.gov/pubmed/25315236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12755 |
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