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Friedreich Ataxia: Failure of GABA-ergic and Glycinergic Synaptic Transmission in the Dentate Nucleus

Atrophy of large neurons in the dentate nucleus (DN) is an important pathological correlate of neurological disability in patients with Friedreich ataxia (FA). Thinning of the DN was quantified in 29 autopsy cases of FA and 2 carriers by measuring the thickness of the gray matter ribbon on stains wi...

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Bibliographic Details
Published in:J Neuropathol Exp Neurol
Main Authors: Koeppen, Arnulf H., Ramirez, Liane, Becker, Alyssa B., Feustel, Paul J., Mazurkiewicz, Joseph E.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294979/
https://ncbi.nlm.nih.gov/pubmed/25575136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0000000000000160
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