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R-Factor-Mediated Resistance to Sulfonamides by a Plasmid-Borne, Drug-Resistant Dihydropteroate Synthase

Evidence was found for the existence of an episome-specified variant of the enzyme dihydropteroate synthase involved in folic acid formation. Since the plasmid-borne enzyme showed a decreased susceptibility for sulfonamide inhibition and was transferable together with resistance to this drug, it is...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
第一著者: Sköld, Ola
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1976
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429472/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/769673/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.9.1.49
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