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R-Factor-Mediated Resistance to Sulfonamides by a Plasmid-Borne, Drug-Resistant Dihydropteroate Synthase
Evidence was found for the existence of an episome-specified variant of the enzyme dihydropteroate synthase involved in folic acid formation. Since the plasmid-borne enzyme showed a decreased susceptibility for sulfonamide inhibition and was transferable together with resistance to this drug, it is...
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| Veröffentlicht in: | Antimicrob Agents Chemother |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
1976
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/769673/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.9.1.49 |
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