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Synthesis and evaluation of arylpiperazines derivatives of 3,5-dioxo-(2H,4H)-1,2,4-triazine as 5-HT(1A)R ligands
5-HT(1A)R agonist or partial agonists are established drug candidates for psychiatric and neurological disorders. We have reported the synthesis and evaluation of a series of high affinity 5-HT(1A)R partial agonist PET imaging agents with greater selectivity over α-1AR. The characteristic of these m...
Gardado en:
| Publicado en: | Bioorg Med Chem Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4294696/ https://ncbi.nlm.nih.gov/pubmed/25182564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.07.048 |
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