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Antibacterial Action of Primaquine: Effects In Vitro on Polypeptide Synthesis and In Vivo on Ribosomes and Ribosomal Ribonucleic Acid

Primaquine inhibited polyphenylalanine formation directed by poly(U) in a cell-free system obtained from Bacillus megaterium only when the drug was preincubated with transfer ribonucleic acid (tRNA), poly(U), or ribosomes. Considerably less inhibition was produced when the ionic strength of the prei...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Autor Principal: Olenick, John G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1975
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429459/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/813574/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.8.6.754
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