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Antibacterial Action of Primaquine: Effects In Vitro on Polypeptide Synthesis and In Vivo on Ribosomes and Ribosomal Ribonucleic Acid

Primaquine inhibited polyphenylalanine formation directed by poly(U) in a cell-free system obtained from Bacillus megaterium only when the drug was preincubated with transfer ribonucleic acid (tRNA), poly(U), or ribosomes. Considerably less inhibition was produced when the ionic strength of the prei...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Autor principal: Olenick, John G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1975
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429459/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/813574/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.8.6.754
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