Antibacterial Action of Primaquine: Effects In Vitro on Polypeptide Synthesis and In Vivo on Ribosomes and Ribosomal Ribonucleic Acid

Primaquine inhibited polyphenylalanine formation directed by poly(U) in a cell-free system obtained from Bacillus megaterium only when the drug was preincubated with transfer ribonucleic acid (tRNA), poly(U), or ribosomes. Considerably less inhibition was produced when the ionic strength of the prei...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Hovedforfatter:	Olenick, John G.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1975
Fag:	Chemistry; Mechanisms of Action and Resistance
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429459/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/813574/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.8.6.754
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