Spectrin Tetramer Formation Is Not Required for Viable Development in Drosophila

The dominant paradigm for spectrin function is that (αβ)(2)-spectrin tetramers or higher order oligomers form membrane-associated two-dimensional networks in association with F-actin to reinforce the plasma membrane. Tetramerization is an essential event in such structures. We characterize the tetra...

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Udgivet i:J Biol Chem
Main Authors: Khanna, Mansi R., Mattie, Floyd J., Browder, Kristen C., Radyk, Megan D., Crilly, Stephanie E., Bakerink, Katelyn J., Harper, Sandra L., Speicher, David W., Thomas, Graham H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294495/
https://ncbi.nlm.nih.gov/pubmed/25381248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.615427
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