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Structural and functional effects of hereditary hemolytic anemia-associated point mutations in the alpha spectrin tetramer site
The most common hereditary elliptocytosis (HE) and hereditary pyropoikilocytosis (HPP) mutations are α-spectrin missense mutations in the dimer-tetramer self-association site. In this study, we systematically compared structural and functional properties of the 14 known HE/HPP mutations located in t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2424163/ https://ncbi.nlm.nih.gov/pubmed/18218854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-122457 |
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