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Increased BDNF protein expression after ischemic or PKC epsilon preconditioning promotes electrophysiologic changes that lead to neuroprotection

Ischemic preconditioning (IPC) via protein kinase C epsilon (PKCɛ) activation induces neuroprotection against lethal ischemia. Brain-derived neurotrophic factor (BDNF) is a pro-survival signaling molecule that modulates synaptic plasticity and neurogenesis. Interestingly, BDNF mRNA expression increa...

詳細記述

保存先:
書誌詳細
出版年:J Cereb Blood Flow Metab
主要な著者: Neumann, Jake T, Thompson, John W, Raval, Ami P, Cohan, Charles H, Koronowski, Kevin B, Perez-Pinzon, Miguel A
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294405/
https://ncbi.nlm.nih.gov/pubmed/25370861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.185
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