SUMO2/3 is associated with ubiquitinated protein aggregates in the mouse neocortex after middle cerebral artery occlusion

Protein modifications cooperatively act to protect the proteome from cellular stress. Focal cerebral ischemia increases protein ubiquitination, resulting in formation of ubiquitin-rich aggregates. A concurrent elevation in small ubiquitin-related modifier (SUMO)-conjugated proteins has also been rep...

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Bibliographic Details
Published in:J Cereb Blood Flow Metab
Main Authors: Hochrainer, Karin, Jackman, Katherine, Benakis, Corinne, Anrather, Josef, Iadecola, Costantino
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
Subjects:
Brief Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294403/
https://ncbi.nlm.nih.gov/pubmed/25352045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.180
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