Poly(ADP-ribose) polymerase-1 inhibition in brain endothelium protects the blood–brain barrier under physiologic and neuroinflammatory conditions

Blood–brain barrier (BBB) dysfunction seen in neuroinflammation contributes to mortality and morbidity in multiple sclerosis, encephalitis, traumatic brain injury, and stroke. Identification of molecular targets maintaining barrier function is of clinical relevance. We used a novel in vivo model of...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Cereb Blood Flow Metab
Päätekijät: Rom, Slava, Zuluaga-Ramirez, Viviana, Dykstra, Holly, Reichenbach, Nancy L, Ramirez, Servio H, Persidsky, Yuri
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294393/
https://ncbi.nlm.nih.gov/pubmed/25248836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.167
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia