Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience

BACKGROUND: Activated PI3K/AKT/mTOR pathway frequently occurs in metastatic or recurrent cervical carcinomas. However, the clinical benefits of matched therapy, a therapeutic approach targeting a specific mutational abnormality, have not yet been established. METHODS: We analyzed the outcomes of pat...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Hou, Ming-Mo, Liu, Xiaochun, Wheler, Jennifer, Naing, Aung, Hong, David, Coleman, Robert L., Tsimberidou, Apostolia, Janku, Filip, Zinner, Ralph, Lu, Karen, Kurzrock, Razelle, Fu, Siqing
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2014
Teme:
Clinical Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294378/
https://ncbi.nlm.nih.gov/pubmed/25426553
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