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Gastrokine 1 induces senescence and apoptosis through regulating telomere length in gastric cancer

The present study aims to investigate whether gastrokine 1 (GKN1) induces senescence and apoptosis in gastric cancer cells by regulating telomere length and telomerase activity. Telomere length, telomerase activity, and hTERT expression decreased significantly in AGS(GKN1) and MKN1(GKN1) cells. Both...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yoon, Jung Hwan, Seo, Ho Seok, Choi, Won Seok, Kim, Olga, Nam, Suk Woo, Lee, Jung Young, Park, Won Sang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294346/
https://ncbi.nlm.nih.gov/pubmed/25344918
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