Gastrokine 1 induces senescence and apoptosis through regulating telomere length in gastric cancer

The present study aims to investigate whether gastrokine 1 (GKN1) induces senescence and apoptosis in gastric cancer cells by regulating telomere length and telomerase activity. Telomere length, telomerase activity, and hTERT expression decreased significantly in AGS(GKN1) and MKN1(GKN1) cells. Both...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Yoon, Jung Hwan, Seo, Ho Seok, Choi, Won Seok, Kim, Olga, Nam, Suk Woo, Lee, Jung Young, Park, Won Sang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2014
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294346/
https://ncbi.nlm.nih.gov/pubmed/25344918
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