Role of Dendritic Cells in the Pathogenesis of Whipple's Disease

Accumulation of Tropheryma whipplei-stuffed macrophages in the duodenum, impaired T. whipplei-specific Th1 responses, and weak secretion of interleukin-12 (IL-12) are hallmarks of classical Whipple's disease (CWD). This study addresses dendritic cell (DC) functionality during CWD. We documented...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Schinnerling, Katina, Geelhaar-Karsch, Anika, Allers, Kristina, Friebel, Julian, Conrad, Kristina, Loddenkemper, Christoph, Kühl, Anja A., Erben, Ulrike, Ignatius, Ralf, Moos, Verena, Schneider, Thomas
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Bacterial Infections
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294246/
https://ncbi.nlm.nih.gov/pubmed/25385798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02463-14
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