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IL12Rβ1ΔTM Is a Secreted Product of il12rb1 That Promotes Control of Extrapulmonary Tuberculosis

IL12RB1 is a human gene that is important for resistance to Mycobacterium tuberculosis infection. IL12RB1 is expressed by multiple leukocyte lineages, and encodes a type I transmembrane protein (IL12Rβ1) that associates with IL12p40 and promotes the development of host-protective T(H)1cells. Recentl...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Ray, Aurelie A., Fountain, Jeffrey J., Miller, Halli E., Cooper, Andrea M., Robinson, Richard T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294230/
https://ncbi.nlm.nih.gov/pubmed/25404030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01230-13
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