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Early Control of Mycobacterium tuberculosis Infection Requires il12rb1 Expression by rag1-Dependent Lineages

IL12RB1 is essential for human resistance to Mycobacterium tuberculosis infection. In the absence of a functional IL12RB1 allele, individuals exhibit susceptibility to disseminated, recurrent mycobacterial infections that are associated with defects in both RAG1-dependent and RAG1-independent hemato...

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Autori principali: Miller, Halli E., Robinson, Richard T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486065/
https://ncbi.nlm.nih.gov/pubmed/22907814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00426-12
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