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The pathophysiology of extracellular hemoglobin associated with enhanced oxidative reactions

Hemoglobin (Hb) continuously undergoes autoxidation producing superoxide which dismutates into hydrogen peroxide (H(2)O(2)) and is a potential source for subsequent oxidative reactions. Autoxidation is most pronounced under hypoxic conditions in the microcirculation and for unstable dimers formed at...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Rifkind, Joseph M., Mohanty, Joy G., Nagababu, Enika
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294139/
https://ncbi.nlm.nih.gov/pubmed/25642190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00500
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