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The pathophysiology of extracellular hemoglobin associated with enhanced oxidative reactions

Hemoglobin (Hb) continuously undergoes autoxidation producing superoxide which dismutates into hydrogen peroxide (H(2)O(2)) and is a potential source for subsequent oxidative reactions. Autoxidation is most pronounced under hypoxic conditions in the microcirculation and for unstable dimers formed at...

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Veröffentlicht in:Front Physiol
Hauptverfasser: Rifkind, Joseph M., Mohanty, Joy G., Nagababu, Enika
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294139/
https://ncbi.nlm.nih.gov/pubmed/25642190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00500
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