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The quaternary hemoglobin conformation regulates the formation of the nitrite-induced bioactive intermediate and the dissociation of nitric oxide from this intermediate

Deoxyhemoglobin reduces nitrite to nitric oxide (NO). In order to study the effect of the hemoglobin quaternary conformation on the nitrite reaction, we compared T-state deoxyhemoglobin with R-state deoxyhemoglobin produced by reacting hemoglobin with carboxypeptidase-A prior to deoxygenation. The n...

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Main Authors: Rifkind, Joseph M., Nagababu, Enika, Ramasamy, Somasundaram
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178107/
https://ncbi.nlm.nih.gov/pubmed/21236353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2011.01.001
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