FBPA PET in boron neutron capture therapy for cancer: prediction of (10)B concentration in the tumor and normal tissue in a rat xenograft model

BACKGROUND: Boron neutron capture therapy (BNCT) is a molecular radiation treatment based on the (10)B (n, α) (7)Li nuclear reaction in cancer cells, in which delivery of (10)B by 4-borono-phenylalanine conjugated with fructose (BPA-fr) to the cancer cells is of critical importance. The PET tracer 4...

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Detalhes bibliográficos
Publicado no:EJNMMI Res
Main Authors: Hanaoka, Kohei, Watabe, Tadashi, Naka, Sadahiro, Kanai, Yasukazu, Ikeda, Hayato, Horitsugi, Genki, Kato, Hiroki, Isohashi, Kayako, Shimosegawa, Eku, Hatazawa, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293470/
https://ncbi.nlm.nih.gov/pubmed/25621196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-014-0070-2
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