Učitavanje...
A Novel Pan-Negative-Gating Modulator of K(Ca)2/3 Channels, Fluoro-Di-Benzoate, RA-2, Inhibits Endothelium-Derived Hyperpolarization–Type Relaxation in Coronary Artery and Produces Bradycardia In Vivo
Small/intermediate conductance K(Ca) channels (K(Ca)2/3) are Ca(2+)/calmodulin regulated K(+) channels that produce membrane hyperpolarization and shape neurologic, epithelial, cardiovascular, and immunologic functions. Moreover, they emerged as therapeutic targets to treat cardiovascular disease, c...
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Izdano u: | Mol Pharmacol |
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Glavni autori: | , , , , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4293453/ https://ncbi.nlm.nih.gov/pubmed/25468883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.095745 |
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