Reversing Translational Suppression and Induction of Toxicity in Pancreatic Cancer Cells Using a Chemoprevention Gene Therapy Approach

Pancreatic cancer is an aggressive disease with limited therapeutic options. Melanoma differentiation–associated gene-7/interleukin-24 (mda-7/IL-24), a potent antitumor cytokine, shows cancer-specific toxicity in a vast array of human cancers, inducing endoplasmic reticulum stress and apoptosis, tox...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Sarkar, Siddik, Quinn, Bridget A., Shen, Xuening, Dent, Paul, Das, Swadesh K., Emdad, Luni, Sarkar, Devanand, Fisher, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293448/
https://ncbi.nlm.nih.gov/pubmed/25452327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.094375
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